Nay Chi Moe Htwe. The Effectiveness of 5% dragon is blood (croton lechleri) extract serum for facial wrinkle reduction. Master's Degree(Dermatology). Mae Fah Luang University. Learning Resources and Educational Media Center. : Mae Fah Luang University, 2022.
The Effectiveness of 5% dragon is blood (croton lechleri) extract serum for facial wrinkle reduction
Effectiveness of 5% dragon is blood (croton lechleri) extract serum for facial wrinkle reduction
Abstract:
Background: Dragons blood is the name given to a dark red resin produced by some plantspecies belonging to the gernera Daemonorops, Dracaena, Croton and Pterocarpus.Croton lechleri contains high level of polyphenol called proanthocyanidines, which means higher anti-oxidant and anti-aging properties. Threemain constituents of dragons blood (Croton lechleri) are proanthocyanidines, taspine, flavonoids. It counteracts the action of free radicals and protects oxidative stress damage to the cells.It also inhibits elastase and collagenase activity and promote elastin activity and collagen leading to delay skin aging process. Therefore, it can treat wrinkles and fine lines, maintain elasticity and moisturization of the skin. At the same time, it prevents skin cancer, hyperpigmentation , wrinkle formation induced by photo damage.
Objective: To study the effectiveness of 5% Dragons blood (Croton lechleri) extract serum for facial wrinkle reduction Materials and Methods: This research is quasi-experimental controlled study with 17 participants and the duration is 12 weeks period. The study population is healthy male and female between the age of 30-5-years old. They need to apply the 5% dragons blood extract serum on both sides of face twice a day for 12 weeks. Follow up appointments would be at 4th, 8th and 12th week. Wrinkles assessment is done by VISIA® Complexion Analysis System for Winkle Score and Cutometer MPA® 580. To measure the improvement, photographs taken with VISIA® Complexion Analysis System evaluated by 3 dermatologists. The volunteers were assessed by physician and questionnaires to detect any adverse effects and participants satisfaction.
Results: 17 participants completed the 12th week period study. The outcome of the mean change of cutometer score were significantly increased (p value < 0.001) in every different visit. Wrinkle evaluation by VISIA was also statistically increased
(p value < 0.001). No adverse effects were detected throughout the study from applying the serum.
Conclusion: 5% Dragons blood (Croton lechleri) extract serum was proven to be safe and effective for facial wrinkle reduction and improving skin elasticity and skin barrier function.
Mae Fah Luang University. Learning Resources and Educational Media Center