Effects of supercritical carbon dioxide extraction (SC-CO2) on the content of triterpenoids in the extracts from Ganoderma lucidum

Name: Tran, Duc Duy.

Organization : Ho Chi Minh City University of Food Industry

Name: Thi, Huu Hanh Pham.

Organization : Ba Ria-Vung Tau University

Name: Phan, Van Man.

Organization : Ba Ria-Vung Tau College of Technology

Email : pvman.dbv@moet.edu.vn

keyword: Supercritical carbon dioxide.

LCSH: Ganoderma lucidum.

; Antioxidant scavenging activity.

; Triterpenoids.

Abstract: This research investigates the effect of SC-CO2 extraction parameters on the triterpenoid recovery from G. lucidum. The SC-CO2 parameters included extraction pressure, extraction temperature, and extraction time. The extraction pressure was varied between 200, 400 and 600 bar, the extraction temperature between 30, 55 and 80 degree celsius, and the extraction time between 30, 75 and 120 min. In this study, the SC-CO2 parameters were first optimized using a response surface methodology (RSM) for maximum triterpenoid recovery. The results showed that the optimal RSM-based SC-CO2 conditions were 430 bar extraction pressure, 54.8 degree celsius extraction temperature and 78.90 min extraction time, achieving the maximum triterpenoid recovery of 1.56 mg/100g. The kinetic behavior of SC-CO2 process was subsequently characterized using a second-order kinetic model under variable extraction pressures and extraction temperatures, given a SC-CO2 time interval. The second-order kinetic models represented well the experimental results of triterpenoid extraction by SC-CO2 method. At these conditions, the triterpenoid extract also exhibited strong scavenging activities with IC50 values of 0.49 mg/mL for the DPPH radical scavenging activity and 0.26 mg/mL for ABTS radical scavenging activity. Thus, triterpenoids extracted from G. lucidum could be regarded as a potential agent for medicinal treatment. The results also suggest that the SC-CO2 extraction can be a useful extraction method for triterpenoid extraction from G. lucidum. "

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2023

Modified: 2565-10-31

Issued: 2022-10-31

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BibliograpyCitation : APPLIED SCIENCE AND ENGINEERING PROGRESS. vol. 16, no. 1 (Jan.-Mar. 2023), p. 1-12.

eng

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