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May Myat Mon. The effects of 5% brassica oleracea var italica extract serum on periorbital wrinkles compared with placebo base serum. Master's Degree(Dermatology). Mae Fah Luang University. Learning Resources and Educational Media Center. : Mae Fah Luang University, 2021.
The effects of 5% brassica oleracea var italica extract serum on periorbital wrinkles compared with placebo base serum
Effects of 5% brassica oleracea var italica extract serum on periorbital wrinkles compared with placebo base serum
Name: May Myat Mon
keyword:
Brassica oleracea var.italica
Classification :.DDC: WR102
;
Broccoli
MeSH:
Skin Aging
-- 275432
MeSH:
Cosmetic Techniques
-- 275433
LCSH:
Skin Aging
-- 275432
LCSH:
Cosmetic Techniques
-- 275433
Abstract:
Background: Wrinkles around the eyes, one of the most prominent signs of aging, be caused by both intrinsic and extrinsic aging process. Potent antioxidant activities can prevent reactive oxygen species (ROS) induced oxidative stress thereby reduce periorbital wrinkles. Broccoli (Brassica oleracea var. italica) have high antioxidant activity, high total phenolic content and high sulforaphane content which can provide anti-aging effect and exhibit free radical-scavenging .
Objective: To study effectiveness and satisfaction of 5% Brassica oleracea var. italica extract to improve periorbital wrinkles.
Methods: Total 16 volunteers, aged 30 to 60 years old male and female who want to reduce their periorbital wrinkles were selected to participate in comparative, double-blind, randomized, controlled and split face clinical trial for 12 weeks. 5% Brassica oleracea var. italica extract and placebo serum were instructed to apply twice daily to periorbital area for 12 weeks. Parameters such as wrinkle evaluation by dermatologists, elasticity and hydration of the skin around the eyes (crows feet area and undereye area) were assessed at the baseline, 4th, 8th, 12th week respectively. No side effects were observed.
Result: Skin elasticity of crows feet area at broccoli extract treated side was significantly increased at 8th and 12th week. Similarly, the elasticity of undereye area showed significantly difference in extract serum side at 4th, 8th and 12th week. Moreover, skin hydration of crows feet area at Broccoli serum treated side was significantly increased at 8th and 12th week. There was a significant increase in skin hydration of undereye area in extract serum treated side at 4th and 12th week respectively.
Conclusion: This study statistically demonstrated that Broccoli extract reduced periorbital wrinkles more than placebo serum when it is applied topically with no harmful side effects. So, 5% Brassica oleracea var. italica extract could be safe and effective to treat periorbital wrinkles.
Mae Fah Luang University. Learning Resources and Educational Media Center
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Name: Tanomkit Pawcsuntorn
Role:
Advisor
Created:
2021
Modified:
2021-12-15
Issued:
2021-12-15
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
WR102 M467e 2020
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Dermatology
Grantor: Mae Fah Luang University
©copyrights Mae Fah Luang University
RightsAccess:
ใช้เวลา
0.027611 วินาที
May Myat Mon
| Title | Contributor | Type |
|---|---|---|
| The effects of 5% brassica oleracea var italica extract serum on periorbital wrinkles compared with placebo base serum
มหาวิทยาลัยแม่ฟ้าหลวง May Myat Mon | Tanomkit Pawcsuntorn | วิทยานิพนธ์/Thesis |
Tanomkit Pawcsuntorn