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Aphinut Srituravanit. Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing. Master's Degree(Dermatology). Thammasat University. Thammasat University Library. : Thammasat University, 2016.
Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing
Name: Aphinut Srituravanit
keyword:
Panthenol
LCSH:
Laser therapy
;
Downtime
Abstract:
Fractional carbon dioxide (FrCO2) laser is effective for atrophic acne scar treatment but the downtime following this procedure is unavoidable. Postoperative topical steroid decreases the risk of this downtime, but in the meantime increases other side effects. The objective of this study was to evaluate the clinical efficacy and safety of the moisturizer containing anti-inflammatory ingredients including 5% Panthenol, Madecassoside, and Copper-Zinc-Manganese (experimental cream) versus 0.02% Triamcinolone Acetonide (TA) cream to improve wound healing and decrease adverse effects and downtime after FrCO2 laser treatment in acne scar. We conducted a double-blind, split face, randomized controlled trial in 20 subjects, with FrCO2 laser treatment on both sides of their faces, and randomly treated with these 2 post-treatment regimens on each side of the face for 7 days. We evaluated the result by using the questionnaires, the expert panel assessment of the photography, downtime and side effects evaluated by subjects, and facial scanning by the Antera 3D device. The result revealed that both the experimental cream and 0.02% TA cream significantly decreased post-laser downtime including swelling, redness, crusting and scaling in 5-7 days. Moreover, they produced lower of the PIH incidence when compared with petrolatum from the previous study. There was no significant different of the efficacies to decrease downtime between the experimental cream and the 0.02% TA cream. Hence, the moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese yielded comparable efficacies to 0.02% TA cream for the improvement of wound healing, decreased adverse reactions and downtime after FrCO2 laser irradiation. This moisturizer could be a novel treatment modality for the reduction of post-ablative laser downtime by using non-steroidal anti-inflammatory agents in a bid to avoid adverse effects from steroids and improve wound healing process
Thammasat University. Thammasat University Library
Address:
BANGKOK
Email:
preserv@tu.ac.th
Name: Suparuj Lueangarun
Role:
advisor
Name: Phubodin Vongtaranavuth
Role:
co-advisor
Created:
2016
Modified:
2021-05-31
Issued:
2021-05-31
วิทยานิพนธ์/Thesis
application/pdf
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Dermatology
Grantor: Thammasat University
©copyrights Thammasat University
RightsAccess:
ใช้เวลา
0.030124 วินาที
Aphinut Srituravanit
| Title | Contributor | Type |
|---|---|---|
| Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing
มหาวิทยาลัยธรรมศาสตร์ Aphinut Srituravanit | Suparuj Lueangarun Phubodin Vongtaranavuth | วิทยานิพนธ์/Thesis |
Suparuj Lueangarun
Phubodin Vongtaranavuth
| Title | Creator | Type and Date Create |
|---|---|---|
| Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing
มหาวิทยาลัยธรรมศาสตร์ Suparuj Lueangarun;Phubodin Vongtaranavuth | Aphinut Srituravanit | วิทยานิพนธ์/Thesis |