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Choowong Auesukaree. Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2020.
Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae
Name: Pannaphan Makarathut
Organization :
Mahidol University. Faculty of Science
Name: Wisuta Chumsawat
Organization :
Mahidol University. Faculty of Science
Name: Piyathida Udchachon
Organization :
Mahidol University. Faculty of Science
Name: Choowong Auesukaree
Organization :
Mahidol University. Faculty of Science
Email :
choowong.aue@mahidol.ac.th
keyword:
Mitochondrial stress
LCSH:
Plant extracts
LCSH:
Saccharomyces cerevisiae
Abstract:
The mitochondria play an important role in several metabolic pathways and ATP synthesis, while the endoplasmic reticulum (ER) is responsible for the synthesis and folding of proteins. Some specific physiological and pathological conditions may lead to the dysfunctional mitochondria and ER, and thereby potentially trigger a number of neurodegenerative diseases. Previously, various herbal extracts have been reported to have protective effects against several cellular stresses. In this study, we aim to identify Thai herbal extracts with high potential for preventing mitochondrial and ER stresses in the yeast Saccharomyces cerevisiae as a model organism. Our results revealed that the growth of yeast cells treated with mitochondrial stress-inducing agent, carbonyl cyanide m-chlorophenyl hydrazone (CCCP), was improved by the supplementations with several aqueous and ethanolic extracts of Thai herbs including Moringa oleifera Lam., Thunbergia laurifolia, Pueraria mirifica, Butea superba Roxb., Zingiber montanum, Acanthus ebracteatus, Mucuna pruriens L., Cissus quadrangularis L., and Centella asiatica L.. In addition, we also found that the aqueous and the ethanolic extracts of Moringa oleifera Lam., Thunbergia laurifolia, Curcuma longa L., Pueraria mirifica, Butea superba Roxb., Boesenbergia rotunda L., Zingiber montanum, Acanthus ebracteatus, Mucuna pruriens L., Cissus quadrangularis L., and Centella asiatica L. could promote the growth of yeast cells treated with ER stress-inducing agent, tunicamycin. Our findings therefore suggest the potential of these herbal extracts for use to inhibit mitochondrial and ER stresses, which may be useful for preventing the diseases associated with these stresses in the future.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2020
Modified:
2021-05-21
Issued:
2021-05-21
บทความ/Article
application/pdf
BibliograpyCitation :
In Thai Society for Biotechnology. The 32nd Annual Meeting of the Thai Society for Biotechnology and International Conference (TSB 2020) (pp. 431-441). Bangkok : The Thai Society for Biotechnology
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.034022 วินาที
Pannaphan Makarathut
| Title | Contributor | Type |
|---|---|---|
| Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pannaphan Makarathut;Wisuta Chumsawat;Piyathida Udchachon;Choowong Auesukaree | บทความ/Article |
Wisuta Chumsawat
| Title | Contributor | Type |
|---|---|---|
| Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pannaphan Makarathut;Wisuta Chumsawat;Piyathida Udchachon;Choowong Auesukaree | บทความ/Article |
Piyathida Udchachon
| Title | Contributor | Type |
|---|---|---|
| Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pannaphan Makarathut;Wisuta Chumsawat;Piyathida Udchachon;Choowong Auesukaree | บทความ/Article |
Choowong Auesukaree
| Title | Contributor | Type |
|---|---|---|
| Macrophage physiology and molecular responses during pseudomonas aeruginosa infection
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Bewarin Taengthet;Pongsak Utaisincharoen;Choowong Auesukaree;Adisak Romsang | บทความ/Article | |
| Screening of Thai herbal extracts with the potential for preventing mitochondrial stress and endoplasmic reticulum stress in saccharomyces cerevisiae
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pannaphan Makarathut;Wisuta Chumsawat;Piyathida Udchachon;Choowong Auesukaree | บทความ/Article | |
| Characterization of lactobacillus spp. isolated from commercial chicken guts
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Teetouch Kajornchaitut;Natharin Ngamwongsatit;Choowong Auesukaree;Watanalai Panbangred;Adisak Romsang | บทความ/Article |