Abstract:
The objective of this study was to prepare the extract from Benjakasorn remedy including Jasminum sambac Ait., Mimusops elengi L., Mesua ferrea L., Mammea siamensis (Miq.) T. Anderson and Nelumbo nucifera Gaertn. by maceration method. DI water and 95% ethanol were compared as solvents. Extractable yield of Benjakasorn extracts were 14.28±0.08 and 11.29±0.35 % w/w, respectively. DI water and the ethanolic extracts gave the total phenolics content of 81.50±9.75 and 478.14±28 mg GAE/g, respectively. DPPH radical scavenging capacities of the extracts reported as IC50 were found to be 108.07±3.37 and 23.41±1.18 µg/ml for DI water and ethanol extraction, respectively. When measuring the ferric reducing ability by FRAP assay the DI water extract showed 91.35±10.32 mg TEAC/g, while the ethanolic extract exhibited 230.87±2.63 mg TEAC/g. Antiglycation activities as IC50 of the extracts from DI water and ethanol were 317.19±11.14 and 320.99±11.65 ug/ml, respectively. Tyrosinase inhibitory activity investigation revealed that the water extract did not show tyrosinase inhibition, while the ethanolic extract inhibited tyrosinase at 129.97±5.57 mg KE/g. Different amounts of ethanolic extract (0.05%, 0.1% and 0.2%) were included into emulsion formulation and stable emulsion after testing was obtained.
This study indicated that the Benjakasorn remedy extract would be promising source for application in cosmetics.