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Piyachat Chuysinuan. Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2017.
Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system
Name: Pimolpun Niamlang
Organization :
Rajamangala University of Technology Rattanakosin. Faculty of Engineering
Email :
pimolpun.kam@rmutr.ac.th
Name: Kadkanok Kangwannawin
Organization :
Rajamangala University of Technology Rattanakosin. Faculty of Engineering
Organization :
Rajamangala University of Technology Rattanakosin. Faculty of Engineering
Name: Piyachat Chuysinuan
Organization :
Chulabhorn Research Institute
keyword:
Semi-solid hydrogel
LCSH:
Polyvinyl alcohol
LCSH:
Curcumin
Abstract:
Semi-solid hydrogel is a form of hydrogel. It is a viscous fluid flowing along the
shape of the applied area. This semi-solid hydrogel features to access a variety of wounds and
can be applied in areas that are difficult to access. In this work, poly(vinyl alcohol) (PVA) with
thermal stability, transparency, biocompatibility, and nontoxicity was used as polymer matrix.
Curcumin was used as a drug which showed effective anti-inflammatory and antioxidant activities.
The PVA solutions were prepared by varying PVA concentrations in range of 3-5 wt.%
in deionized water. Borax was used as a crosslink agent, and the amount was fixed at 4% w/w
(based on the weight of PVA). The optimum ratio was determined from their swelling ratio
(%). The results indicated that the semi-solid hydrogel obtained from 4.5wt% of PVA provided
a good handling characteristic and showed the lowest swelling ratio (1,700±68%) among others.
The curcumin-loaded PVA semi-solid hydrogels were tested for thier in vitro release and
antioxidant activity. The obtained results suggested that the curcumin-loaded PVA semi-solid
hydrogel possess a potential for use as transdermal drug delivery system.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2017
Modified:
2562-08-19
Issued:
2019-08-19
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol and King Mongkut's University of Technology North Bangkok Faculty of Applied Science. Pure and Applied Chemistry International Conference (PACCON 2017) (pp.1096-1099). Bangkok : Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.031854 วินาที
Pimolpun Niamlang
| Title | Contributor | Type |
|---|---|---|
| Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pimolpun Niamlang;Kadkanok Kangwannawin;Thatsawan Phaengkhamhaeng;Piyachat Chuysinuan | บทความ/Article |
Kadkanok Kangwannawin
| Title | Contributor | Type |
|---|---|---|
| Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pimolpun Niamlang;Kadkanok Kangwannawin;Thatsawan Phaengkhamhaeng;Piyachat Chuysinuan | บทความ/Article |
Thatsawan Phaengkhamhaeng
| Title | Contributor | Type |
|---|---|---|
| Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pimolpun Niamlang;Kadkanok Kangwannawin;Thatsawan Phaengkhamhaeng;Piyachat Chuysinuan | บทความ/Article |
Piyachat Chuysinuan
| Title | Contributor | Type |
|---|---|---|
| ฤทธิ์ทางชีวภาพของสารสกัดข้าวทับทิมชุมแพเพื่อใช้ประโยชน์ทางเครื่องสำอาง
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| Development of semi-solid hydrogel from poly(vinyl alcohol) for use as transdermal drug delivery system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pimolpun Niamlang;Kadkanok Kangwannawin;Thatsawan Phaengkhamhaeng;Piyachat Chuysinuan | บทความ/Article | |
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