Natural thin film doped with oxyresveratrol for anti-aging and whitening agent of transdermal patch

Name: Piyanan Thuamwong

Organization : King Mongkut’s University of Technology Thonburi. Faculty of Science

Name: Nakorn Niamnont

Organization : King Mongkut’s University of Technology Thonburi. Faculty of Science

Email : nakorn.nia@kmutt.ac.th

keyword: Oxyresveratrol

LCSH: Thin film devices -- Materials

; Artocarpus lakoocha Roxb

LCSH: Cellulose acetate

; Phosphate buffer saline

Abstract: Oxyresveratrol was extracted from the heartwood of Arthocarpus Lakoocha Roxb, which provided antioxidant and anti-tyrosinase effects. The oxyresveratrol with the concentration of 0.1 %w/w was loaded into PCL/CA blended solutions, which was prepared by mixing 9 %w/w poly(ε-caprolactone) (PCL) with 17 %w/w cellulose acetate (CA). The output was used to make thin film according to solvent-casting technique and characterized its surface by using SEM images. The release of oxyresveratrol from the thin film materials, the effectiveness of anti-tyrosinase and antioxidant activity were also studied. The release profiles were analyzed by using the total immersion method, which was 0.5 %v/v tween 80, 10 %v/v methanol in 10 mM phosphate buffer saline (PBS) at pH 7.4. The results showed that 1:3 w/w PCL/CA blended solution exhibited the highest anti-tyrosinase and antioxidant activity at 88 % and 78%, respectively. The results suggested that thin film materials doped with oxyresveratrol could be applied as a non-invasive whitening and anti-aging material, which highlighted its potential for an easy-to-use transdermal patch application.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2017

Modified: 2562-08-15

Issued: 2019-08-15

บทความ/Article

application/pdf

BibliograpyCitation : In Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol and King Mongkut's University of Technology North Bangkok Faculty of Applied Science. Pure and Applied Chemistry International Conference (PACCON 2017) (pp.866-871). Bangkok : Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol

eng

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