The study on effectiveness of gynura procumbens leaves on decreasing the level of hba1c and fasting blood glucose in prediabetes patients at Chonburi province
Study on effectiveness of gynura procumbens leaves on decreasing the level of hba1c and fasting blood glucose in prediabetes patients at Chonburi province
Abstract:
The objective of this research was to study the effectiveness of Gynura procumbens leaf on lowering the level of HbA1C and fasting blood glucose in pre-diabetes patients. The experiment was conducted by using 52 volunteers which has been separated into 3 groups for three different chemicals tested; Methyl cellulose, Gynura procumbens 1600 mg and metformin500 mg. Each group of volunteers took one of the chemicals in combination with diet exercise recommendation. The results were determined from 15 volunteers of each group for statistical analysis.
The result showed that there was significantly decreasing of HbA1C in patients after taking Gynura procumbens for 12 weeks.As compared to Methyl cellulose and metformin the decreasing of HbA1C level by Gynura procumbens was lower than the two chemicals tested but no statistical significant. Gynura procumbens did not have any effect in lowering fasting blood glucose significantly. Furthermore it was also found that Gynura procumbens did not significantly decrease mean arterial pressure, body mass index, blood cholesterol and blood triglyceride level.
There were no toxicity to liver and kidney when measuring the activity levels of Alanine aminotransferase and creatinine,respectively after taking Gynura procumbens 1600 mg per day for 12 weeks.