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Saravut Ruangprapavut. The clinical efficacy of topical platelet-rich plasma with fractional radiofrequency microneedle treatment for atrophic acne scar. Master's Degree(Dermatology). Mae Fah Luang University . : Mae Fah Luang University , 2017.
The clinical efficacy of topical platelet-rich plasma with fractional radiofrequency microneedle treatment for atrophic acne scar
Clinical efficacy of topical platelet-rich plasma with fractional radiofrequency microneedle treatment for atrophic acne scar
Name: Saravut Ruangprapavut
Organization :
Mae Fah Luang University
keyword:
Platelet-rich plasma
LCSH:
Skin Diseases
-- therapy
Classification :.LCCS: WR650
LCSH:
Radio Waves
-- therapeutic use
LCSH:
Platelet-Rich Plasma
Abstract:
BACKGROUND: Acne scarring is a frequent complication of acne vulgaris. Recently, a novel fractional radiofrequency microneedle system has been introduced for the purpose of treating acne scars. Additionally, Platelet-rich plasma has potential benefits in treatment of acne scars. For this research, we evaluated efficacy and safety of the combination technique for acne scars treatment.
OBJECTIVE: To study about efficacy and other effects of the combination treatments on atrophic acne scars.
MATERIALS AND METHODS: It is experimental study. 19 participants with atrophic acne scars age between 18 45 years old were enrolled then treated with fractional radiofrequency microneedle (FRM) and platelet-rich plasma (PRP) at week 0, 4th and 8th. After that, volunteers were followed up at week 4th and 8th. Clinical outcome which took by VISIA® complexion analysis was evaluated by 2 independent physicians before and after each treatment and also skin elasticity was evaluated by Cutometer® MPA 580. Moreover, Sebum production was evaluated by Sebumeter® SM815. Finally, volunteers satisfaction was evaluated by questionnaire after the last follow-up. Adverse reactions were also recorded.
RESULTS: 19 participants were enrolled. 1 patient was drop out at the second treatment (4th week), and 18 participants were evaluated. Acne grading between baseline and follow-up both times time were statistically different with p<0.001. Moreover, There were significant difference of improvement score at week 4th and 8th follow-ups (p=0.002). There were statistical significance (p=0.014) had increase elasticity at 8th week follow-ups. For sebum production, there were statistical significance (p=0.043) had decrease sebum production at 8th week follow-ups. At the last time follow-up, participants had most scores for improvement of acne scar as satisfied (38.89%).
CONCLUSION: Combination of FRM and PRP treatment can be effective treatments for atrophic acne scars. Cutometer found more elasticity at 2 month follow-up. Sebumeter found less sebum production at 2 month follow-up. Longer follow-ups for next studies should be done for acne scar treatment.
The author has indicated no interest with commercial supporters.
Mae Fah Luang University
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Name: Paisal Rummaneethorn
Role:
Advisor
Created:
2017
Issued:
2561
Modified:
2020-01-21
Issued:
2018-09-13
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
Thesis WR650 S243c 2017
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Dermatology
Grantor: Mae Fah Luang University
©copyrights Mae Fah Luang University
RightsAccess:
ใช้เวลา
0.031861 วินาที
Saravut Ruangprapavut
| Title | Contributor | Type |
|---|---|---|
| The clinical efficacy of topical platelet-rich plasma with fractional radiofrequency microneedle treatment for atrophic acne scar
มหาวิทยาลัยแม่ฟ้าหลวง Saravut Ruangprapavut | Paisal Rummaneethorn, M. D. | วิทยานิพนธ์/Thesis |
Paisal Rummaneethorn