Transport of Folate cofactors by Plasmodium Falciparum infected Red blood cells

การขนส่งโฟเลตเข้าสู่เม็ดเลือดแดงที่ติดเชื้อพลาสโมเดียมฟัลซิพารั่ม

Name: Sataporn Suttikulpitug

MeSH: Erythrocytes

MeSH: Infection

MeSH: Plasmodium Falciparum

Abstract: Study of folate uptake by P.falciparum infected red blood cells indicated that the increase in rated of uptake resulted form the intracellular parasites. Folate uptake was highest at the schizont stage and was icreased with percent parasitemia. The uptake was neither a carrier-mediated nor an active transport because it could not be competitively inhibited by folate analogues, was not dependent on cellular energy, and showed no saturation with folate concentration in the transporting medium. The data primarily suggested that the uptake was through pores formed during infection by the malarial parasite. From the present study the existence of a possible folate salvage pathway in P.falciparum could not be demonstrated.

Mahidol University. Mahidol University Library and Knowledge Center

Address: NAKHONPATHOM

Email: liwww@mahidol.ac.th

Name: Yongyuth Yuthavong

Role: Thesis Advisors

Name: Pintip Ruenwongsa

Role: Thesis Advisors

Name: Dhirayos Wititsuwannakul

Role: Thesis Advisors

Created: 1989

Modified: 2018-03-08

Issued: 2018-03-08

วิทยานิพนธ์/Thesis

application/pdf

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Biochemistry

Grantor: Mahidol University

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1	10933815-eng.pdf	166.5 KB
2	10933815-tha.pdf	175.26 KB
3	10933815.pdf	21.54 MB

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