Chayanid Bunsaisup. A comparative study on the efficacy of non-thermal plasma device combined with topical treatment alone for moderate facial acne vulgaris in Thais. Master's Degree(Dermatology). Mae Fah Luang University. The Learning Resources and Education Media Center. : Mae Fah Luang University , 2015.
A comparative study on the efficacy of non-thermal plasma device combined with topical treatment alone for moderate facial acne vulgaris in Thais
Comparative study on the efficacy of non-thermal plasma device combined with topical treatment alone for moderate facial acne vulgaris in Thais
Abstract:
Background: Acne is common problem in dermatologic clinic. Most of the cases were found in teenagers. In many cases showed that Thai conventional treatment may not be effective therapy. There are many alternative treatments which are new technology and reported to be safe, for instance non-thermal plasma. Plasma medicine has many researches showing their efficiency and safety in treatment of acne with minimal side effect
Objective: To examine the efficacy of plasma technology in enhancing treatment of acne vulgaris (in term of duration) compared with the topical treatment of acne.(Split face controlled trial).
Material and methods: Thirty Thai volunteers were enrolled and had moderate facial acne vulgaris at both sides of face. Randomly assigned for treatment by non-thermal plasma device combined with topical treatment and topical treatment alone in each sides. All volunteers received topical treatment for applying full-face. Half of face would receive non-thermal plasma once a week for 4 weeks. Clinical evaluation was done at week 4, 8, 12 by using photographs of VISIA complexion analysis, acne grading and acne lesion counting. Side effects and satisfaction were assessed by questionnaire.
Results: Twenty eight volunteers completed the study. Both sides of face had statistically significant decrease from baseline in acne grade and acne lesion count. The side of treatment by non-thermal plasma combined with topical treatment had better outcome than topical treatment alone in term of duration, there was statistically significant difference at week 4, 8, 12 when evaluated by comparing acne grade and acne lesion count. The adverse effects resemble between two groups. The satisfaction score of both groups was average to excellent satisfaction.
Conclusion: Non-thermal plasma device combined with topical treatment could enhance the therapeutic efficacy in treatment of moderate facial acne vulgaris in Thais.
Mae Fah Luang University. The Learning Resources and Education Media Center