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Anek Sony. The Effect of irvingia gabonensis on postrandial glycemic control and insulin sensitivity in non-diabetic subjects. Master's Degree(Anti-Aging and Regenerative Medicine). Mae Fah Luang University . : Mae Fah Luang University , 2013.
The Effect of irvingia gabonensis on postrandial glycemic control and insulin sensitivity in non-diabetic subjects
Effect of irvingia gabonensis on postrandial glycemic control and insulin sensitivity in non-diabetic subjects
Name: Anek Sony
Organization :
Mae Fah Luang University
keyword:
Irvingia gabonensis
Classification :.LCCS: Nutrition Disorders -- prevention & control
Classification :.;: Diet Therapy -- methods
Abstract:
Recent epidemiology study has estimated that the prevalence of diabetes is increasing at an extremely higher rate. One of the most well known oriental herbs is Irvingia Gabonensis, which has been shown to be efficacious for the treatment and prevention of diabetes in rat (Omoruyi F, Adamson I. Department of Biochemistry, University of Benin, Nigeria). The purpose of this study is to evaluate the influence of Irvingia Gabonensis on postprandial plasma glucose level and insulin sensitivity. This
study was conducted on 14 subjects, with a crossover design. Subjects were initially screened for non-diabetic status (FBS: < 126 mg/dL). Subjects were randomized to drink either 100ml of Irvingia Gabonensis or water 30 minutes prior to 75 grams sucrose solution. Venous blood samples were collected before sucrose ingestion (time point 0) and at 30, 60, 90, 120, and 150 minutes after. After OGTT, participants kept a diary of severity of abdominal and other symptoms score scales. The author found that the Irvingia Gabonensis sample group tends to have a lower level of plasma glucose, serum insulin concentrations compared to the controlled group, with significant difference of plasma glocose at 30 (P=0.015), 60 (P=0.022),120 (0.012) and 150 (P<0.01) minutes. The mean difference of the incremental glucose level at each time point also tends to be lower for the Irvingia Gabonensis group, with significant difference at 30-min time point (P< 0.01), 60-min time point (P=0.008), 90-min time point (P=0.039), 120-min time point (P=0.019), 150-min time point (P<0.001). To conclude, in non-diabetic subjects,
consumption of Irvingia Gabonensis aid in postprandial glycemic control during the first 30, 60, 120 and 150 minutes after meal. Irvingia Gabonensis does not influence the physiological insulin sensitivity and does not cause significant adverse events.
Mae Fah Luang University
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Name: Werner Kurotschka
Role:
Advisor
Name: Phaisit Trakulkongsmut
Role:
Co-Advisor
Created:
2013
Modified:
2020-03-30
Issued:
2015-02-11
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
Thesis WB400 A578e 2013
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Anti-Aging and Regenerative Medicine
Grantor: Mae Fah Luang University
ใช้เวลา
0.041623 วินาที
Anek Sony
| Title | Contributor | Type |
|---|---|---|
| The Effect of irvingia gabonensis on postrandial glycemic control and insulin sensitivity in non-diabetic subjects
มหาวิทยาลัยแม่ฟ้าหลวง Anek Sony | วิทยานิพนธ์/Thesis |
Werner Kurotschka
Phaisit Trakulkongsmut
| Title | Creator | Type and Date Create |
|---|---|---|
| The effect of daily consumption of boiled and fried egg on cholesterol level in overweight Thai men
มหาวิทยาลัยแม่ฟ้าหลวง Professor Dr. Werner Kurotschka;Lecturer Phaisit Trakulkongsmut | Mongkol Kaewsutas | วิทยานิพนธ์/Thesis |
| The efficacy of oral alpha-lipoic acid for physiotherapy supplementation in the treatment of sciatic neuropathic pain
มหาวิทยาลัยแม่ฟ้าหลวง Werner Kurotschka;Phaisit Trakulkongsmut | Aree Jaroenchaichana | วิทยานิพนธ์/Thesis |
| Effect of syzygium cumini (L.) skeels seed extract on lowering blood glucose level in Thai people with impaired fasting glucose
มหาวิทยาลัยแม่ฟ้าหลวง Werner Kurotschk;Phaisit Trakulkongsmut | Wannaphorn Pourprasert | วิทยานิพนธ์/Thesis |