Jiraporn Punyoo. A comparison of the effects of endotracheal suctioning with and without normal saline instillation on physiologic changes in pediatric patients with mechanical ventilation. Master's Degree(Pediatric Nursing ). Mahidol University. : Mahidol University, 2006.
A comparison of the effects of endotracheal suctioning with and without normal saline instillation on physiologic changes in pediatric patients with mechanical ventilation
Abstract:
This crossover-experimental research compared of the effects of endotracheal
suctioning with and without normal saline instillation on physiologic changes in
pediatric patients with mechanical ventilation. The conceptual framework was based
on biomedical knowledge about pathophysiology of oxygenation and ventilation
during endotracheal suctioning. Sixty-five suctionings from fifty-eight pediatric
patients, who were admitted to the Pediatric Intensive Care Unit (PICU) in
Ramathibodi Hospital during July 2005 to January 2006, were selected by purposive
sampling. The crossover-experimental design was used to compare the mean changes
in oxygen saturation, end-tidal CO2, heart rate, and mean blood pressure between the
subjects after endotracheal suctioning. Each subject was exposed to both methods: the
endotracheal suctioning with and without normal saline instillation. The sequence of
the experimental method for eligible subjects was assigned by drawing lots (number 1
to 65) without replacement. The duration between each suctioning method was 3
hours before starting another method. Data were analyzed using with SPSS/FW
program in descriptive statistics, paired t-test, and wilcoxon signed ranks test.
The results revealed that oxygen saturation after endotracheal suctioning with
normal saline instillation was decreased more than after the endotracheal suctioning
without normal saline instillation over time with a statistically significant difference
(p<.05). End-tidal CO2, heart rate, and mean blood pressure after endotracheal
suctioning with normal saline instillation were increased more than after the
endotracheal suctioning without normal saline instillation over time with a statistically
significant difference (p<.05).
This study suggests that the instillation of normal saline before endotracheal
suctioning resulted in decrease of oxygen saturation, increase of end-tidal CO2, heart
rate and blood pressure. Thus, these data should be used to develop an endotracheal
suctioning clinical nursing practice guideline.