Aerugine, an Antibiotic from Streptomyces fradiae Strain SU-1

Name: Busaya Apichaisataienchote

Organization : Kasetsart University. Department of Plant Pathology (Tropical Agriculture, International Program)

Name: Vichai Korpraditskul

Organization : Kasetsart University. Department of Plant Pathology (Tropical Agriculture, International Program)

Name: Fotso, Serge

Organization : University of Goettinggen. Department of Organic and Biomolecular Chemistry.

Name: Laatsch, Hartmut

Organization : University of Goettinggen. Department of Organic and Biomolecular Chemistry.

keyword: aerugine

; thiazoline

; Streptomyces fradiae

; Colletotrichum gloeosporioides

; Phytophthora parasitica

Abstract: The antibiotic aerugine (4-hydroxymethyl-2-(2-hydroxyphenyl)-2-thiazoline) was isolated from the culture filtrate of Streptomyces fradiae strain SU-1 and purified by Sephadex LH-20 and silica gel column chromatography. The structure was determined by detailed interpretation of 1H, 13C NMR and mass spectra. The minimum inhibitory concentrations (MIC) of aerugine were 12.5 ?l/ml determined against both Colletotrichum gloeosporioides and Phytophthora parasitica. It completely inhibited conidial germination of C. gloeosporioides and inhibited encysted zoospore germination of P. parasitica.

Kasetsart University. Office of the University Library

Address: BANGKOK

Email: tdckulib@ku.ac.th

Created: เม.ย.-มิ.ย. 2549

Modified: 2009-09-07

Issued: 2009-09-07

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วิทยาสารเกษตรศาสตร์ (สาขาวิทยาศาสตร์), 40(2) หน้า 335-340

eng

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